BiP inducer X
CAS No. 101714-41-4
BiP inducer X ( BIX )
产品货号. M27965 CAS No. 101714-41-4
BiP inducer X is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥316 | 有现货 |
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10MG | ¥518 | 有现货 |
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25MG | ¥1037 | 有现货 |
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50MG | ¥1798 | 有现货 |
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100MG | ¥3013 | 有现货 |
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200MG | ¥4447 | 有现货 |
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500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称BiP inducer X
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述BiP inducer X is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.
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产品描述BiP inducer X is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.(In Vitro):Pretreatment of BiP inducer X (5?μM; 12 hours) inhibits cell death induced by ER stress involving inhibited activation of caspases 3/7 and 4. In SK-N-SH cells, BiP inducer X (5?μM; 0-12 hours) increases BiP protein and is mediated by activation of ER stress response elements (ERSEs) through the ATF6 pathway.(In Vivo):In male adult ddY mice, BiP inducer X (20?μg) reduces ER stress-induced apoptosis induced in the penumbra by MCA occlusion. BiP inducer X reduces the insults due to cerebral infarction.
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同义词BIX
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通路Apoptosis
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靶点Apoptosis
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受体NFAT5
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研究领域——
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适应症——
化学信息
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CAS Number101714-41-4
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分子量209.2
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分子式C9H7NO3S
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纯度>98% (HPLC)
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溶解度——
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SMILESOc1ccc(cc1O)C(=O)CSC#N
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Han EJ, et al. Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors. EBioMedicine. 2017 Apr;18:261-273.
产品手册
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